Day hotels available in Otay Mesa: 16Sort by:PopularityPorto Vista Hotel In Little ItalyPreviousNextPool access includedPorto Vista Hotel In Little ItalySee on mapLittle Italy4.2/5 | 40 ReviewsFree cancellationPayment at the hotel£69-51%£140 per nightFree cancellationPayment at the hotelFrom£69-51%£140 per nightPrevious8am - 2pm10am - 5pm3pm - 11pmNextSave 10% on your first booking*Only on selected hotels with online paymentCode :FIRST10*Only on selected hotels with online paymentThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottPreviousNextThe Guild Hotel, San Diego, A Tribute Portfolio Hotel by MarriottSee on mapCore-Columbia4.5/5 | 16 ReviewsFree cancellationPayment at the hotel£104-33%£155 per nightFree cancellationPayment at the hotelFrom£104-33%£155 per nightPrevious8am - 2pm10am - 5pmNextDays Inn by Wyndham San Diego/Downtown/Convention CenterPreviousNextDays Inn by Wyndham San Diego/Downtown/Convention CenterSee on mapCore-Columbia4/5 | 32 ReviewsFree cancellationPayment at the hotel£62-58%£147 per nightFree cancellationPayment at the hotelFrom£62-58%£147 per nightPrevious9am - 4pmNextMotel 6-San Diego, CA - DowntownPreviousNextMotel 6-San Diego, CA - DowntownSee on mapCoronado4.1/5 | 10 ReviewsFree cancellationPayment at the hotel£47-34%£70 per nightFree cancellationPayment at the hotelFrom£47-34%£70 per nightPrevious8am - 2pm9am - 4pm1pm - 7pm5pm - 10pmNextManchester Grand Hyatt San DiegoPreviousNextPool access includedManchester Grand Hyatt San DiegoSee on mapMarina4.7/5 | 33 ReviewsFree cancellationPayment at the hotel£174-36%£271 per nightFree cancellationPayment at the hotelFrom£174-36%£271 per nightPrevious9am - 5pm11am - 6pmNextResidence Inn by Marriott San Diego DowntownPreviousNextPool access includedResidence Inn by Marriott San Diego DowntownSee on mapLittle Italy4.6/5 | 14 ReviewsFree cancellationPayment at the hotel£116-35%£178 per nightFree cancellationPayment at the hotelFrom£116-35%£178 per nightPrevious10am - 5pmNextHoliday Inn Express - Downtown San Diego, an IHG HotelPreviousNextPool access includedHoliday Inn Express - Downtown San Diego, an IHG HotelSee on mapCortez HillFree cancellationPayment at the hotel£96-39%£157 per nightFree cancellationPayment at the hotelFrom£96-39%£157 per nightPrevious10am - 5pmNextBaymont by Wyndham San Diego DowntownPreviousNextBaymont by Wyndham San Diego DowntownSee on mapCore-Columbia4.4/5 | 12 ReviewsFree cancellationPayment at the hotel£58-56%£131 per nightFree cancellationPayment at the hotelFrom£58-56%£131 per nightPrevious10am - 4pmNextThe Bristol Hotel San DiegoPreviousNextThe Bristol Hotel San DiegoSee on mapCore-Columbia4.7/5 | 7 ReviewsFree cancellationPayment at the hotel£81-26%£108 per nightFree cancellationPayment at the hotelFrom£81-26%£108 per nightPrevious7am - 1pmNextCourtyard by Marriott San Diego DowntownPreviousNextCourtyard by Marriott San Diego DowntownSee on mapCore-Columbia4.8/5 | 13 ReviewsFree cancellationPayment at the hotel£139Free cancellationPayment at the hotelFrom£139-17%£167 per nightPrevious7am - 6pm9am - 4pm10am - 6pmNextHampton Inn San Diego-DowntownPreviousNextPool access includedHampton Inn San Diego-DowntownSee on mapSan Diego, CA4.6/5 | 5 ReviewsFree cancellationPayment at the hotel£112-52%£232 per nightFree cancellationPayment at the hotelFrom£112-52%£232 per nightPrevious10am - 4pmNextMargaritaville Hotel San Diego Gaslamp QuarterPreviousNextPool access includedMargaritaville Hotel San Diego Gaslamp QuarterSee on mapEast Village4.9/5 | 22 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFrom£77-67%£232 per nightSold out offersKimpton Hotel Palomar San DiegoPreviousNextPool access includedKimpton Hotel Palomar San DiegoSee on mapCore-Columbia4.8/5 | 7 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFrom£0Sold out offersThe El Cordova HotelPreviousNextPool access includedThe El Cordova HotelSee on mapCoronadoFree cancellationPayment at the hotelFree cancellationPayment at the hotelFrom£0Sold out offersRamada by Wyndham San Diego National CityPreviousNextPool access includedRamada by Wyndham San Diego National CitySee on mapNational City4.1/5 | 12 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFrom£0Sold out offersThe Westin San Diego BayviewPreviousNextPool access includedThe Westin San Diego BayviewSee on mapCore-Columbia4.7/5 | 29 ReviewsFree cancellationPayment at the hotelFree cancellationPayment at the hotelFrom£0Sold out offers1